The house in Tolmachev (Kolobovskaya) street where the museum is situated belonged to D.N. Mamin-Sibiryak's wife M.Ya. Alekseeva. The write lived there from 1878 to 1891. His best novels ("Privalov's Millions", "Gornoe gnezdo" [Mountain Nest]) were created there. Besides, the creative intellectuals (writers, artists, musicians) of Yekaterinburg gathered there too.
The permanent exposition of the museum presents the information about lives and works of the Ural writers of the 19th century (I.I. Varakin, I.I. Zheleznov, K.D. Nosilov, A.A. Kirpishchikova, A.G. Turkin, E.A. Slovtsova-Kamskaya, P.I. Zayakin-Uralsky, I.F. Kolotovkin, A.S. Sigov-Pogorelov) and literary works of art of that time. There are some materials about Russian famous literary men's visits to the Urals such as V.N. Tatishchev, V.I. Dal, V.A. Zhukovsky, A.N. Radishchev, P.P. Sumarokov, V.K. Kukhelbeker, N.G. Garin-Mikhaylovsky, S.Ya. Elpatyevsky.
In the halls of the museum the image of Yekaterinburg of the 19th century with its saturated spiritual life and the literature as its main base is restored. Here one can be acquainted with the documents telling them about famous citizens of Yekaterinburg, Mamin-Sibiryak's contemporaries and with the theatrical and musical life of the city of that time